Nucleic Acid Extraction.
Discover the value of our DNA/RNA solutions tailored to your research project.
At the forefront of genetic research, we pride ourselves on providing cutting-edge solutions that deliver the highest quality DNA and RNA samples for your laboratory needs. Our dedicated team operates under a strict Quality Management System to ensure the highest standards of genetic material extraction.
Whether your focus is genomics, diagnostics, or haematology, our reliable nucleic acid extraction solutions support your research with precision and excellence.
We can offer solutions for your SNP genotyping, whole genome and whole exome sequencing needs (SNP, WGS & WES) through our on-site market-leading sequencing partners.
DNA Extraction
For DNA extraction we use a magnetic bead technology and customised commercial kits for both Thermofisher King Fisher Flex and Perkin Elmer Chemagic 360 platform supporting automated extraction of a variety of human liquid biopsy samples and input volumes.
All samples are processed in either a 24 or 96 SBS format with a range of sample types and volumes (200 μl, 400 μl, 500 μl, 2.000 μl) of blood, saliva and blood fractionations for DNA isolation.
RNA Extraction
For RNA extraction we use fully automated spin-column technology with QIAGEN QIAcube systems.
DNA/RNA Quantification
DNA/RNA quantification is crucial in various molecular biology and genetics applications, including DNA sequencing, gene expression analysis, PCR (polymerase chain reaction), and many other molecular techniques.
Accurate quantification is essential to ensure the success of molecular biology experiments, it helps researchers use the correct amount of genetic material and obtain reliable and reproducible results while ensuring optimal use of precious samples. Our services meet the demands of any downstream analyses.
At UKBC we have fully automated quantification systems employing the following techniques:
- Spectrophotometric absorbance using Unchained Labs’ Lunatic platform.- PicoGreentm measurement.
- RiboGreentm measurement.
- Agarose gel electrophoresis.
DNA Normalisation
DNA normalisation allows for a collection of samples that have gone through an extraction process to be presented to a downstream assay or processed with a standard concentration and volume, while being economic with your source nucleic acid permitting further work.
Our fully automated DNA normalisation services are provided using Tecan Freedom Evo liquid handling workstations that incorporate absorbance and PicoGreentm quantification systems. DNA can be normalised from any starting labware to any labware required for downstream analysis. These fully automated systems record all associated data and track samples using barcode readers.
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